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... > Enzymes and Coenzymes > Enzymes > Hydrolases > Peptide Hydrolases > Endopeptidases > Metalloendopeptidases > Collagenases > Microbial Collagenase
... > Enzymes and Coenzymes > Enzymes > Hydrolases > Peptide Hydrolases > Metalloproteases > Metalloendopeptidases > Collagenases > Microbial Collagenase

Preferred term

Microbial Collagenase  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Clostridiopeptidase A
  • Clostridium histolyticum Collagenase
  • Clostridium histolyticum, Collagenase
  • Collagenase Clostridium histolyticum
  • Collagenase, Clostridium histolyticum
  • Collagenase, Microbial
  • Collalysine
  • histolyticum, Collagenase Clostridium
  • Nucleolysin

Scope note

  • A metalloproteinase which degrades helical regions of native collagen to small fragments. Preferred cleavage is -Gly in the sequence -Pro-Xaa-Gly-Pro-. Six forms (or 2 classes) have been isolated from Clostridium histolyticum that are immunologically cross-reactive but possess different sequences and different specificities. Other variants have been isolated from Bacillus cereus, Empedobacter collagenolyticum, Pseudomonas marinoglutinosa, and species of Vibrio and Streptomyces. EC 3.4.24.3.

History note

  • 94; was CLOSTRIDIUM HISTOLYTICUM COLLAGENASE 1991-93; was CLOSTRIDIOPEPTIDASE A 1963-90

In other languages

URI

http://www.yso.fi/onto/mesh/D003012

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