Concept information
Preferred term
Cocaine
Type
-
Topical Descriptor
Broader concept
Narrower concepts
Entry terms
- Cocaine Hydrochloride
- Hydrochloride, Cocaine
Note
- cocaine derivatives = COCAINE /analogs; CRACK COCAINE, COCAINE SMOKING and COCAINE-RELATED DISORDERS are available
Scope note
- An alkaloid ester extracted from the leaves of plants including coca. It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in the eye, ear, nose, and throat. It also has powerful central nervous system effects similar to the amphetamines and is a drug of abuse. Cocaine, like amphetamines, acts by multiple mechanisms on brain catecholaminergic neurons; the mechanism of its reinforcing effects is thought to involve inhibition of dopamine uptake.
History note
- COCAINE DERIVATIVES was see under COCAINE 1975-77; was see under TROPANES 1969-74
URI
http://www.yso.fi/onto/mesh/D003042
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