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... > Digestive System Diseases > Gastrointestinal Diseases > Intestinal Diseases > Colonic Diseases > Colorectal Neoplasms > Colorectal Neoplasms, Hereditary Nonpolyposis
... > Digestive System Diseases > Gastrointestinal Diseases > Intestinal Diseases > Intestinal Neoplasms > Colorectal Neoplasms > Colorectal Neoplasms, Hereditary Nonpolyposis
... > Digestive System Diseases > Gastrointestinal Diseases > Gastrointestinal Neoplasms > Intestinal Neoplasms > Colorectal Neoplasms > Colorectal Neoplasms, Hereditary Nonpolyposis
... > Digestive System Diseases > Digestive System Neoplasms > Gastrointestinal Neoplasms > Intestinal Neoplasms > Colorectal Neoplasms > Colorectal Neoplasms, Hereditary Nonpolyposis
... > Neoplasms > Neoplasms by Site > Digestive System Neoplasms > Gastrointestinal Neoplasms > Intestinal Neoplasms > Colorectal Neoplasms > Colorectal Neoplasms, Hereditary Nonpolyposis
... > Digestive System Diseases > Gastrointestinal Diseases > Intestinal Diseases > Rectal Diseases > Colorectal Neoplasms > Colorectal Neoplasms, Hereditary Nonpolyposis
Congenital, Hereditary, and Neonatal Diseases and Abnormalities > Genetic Diseases, Inborn > Neoplastic Syndromes, Hereditary > Colorectal Neoplasms, Hereditary Nonpolyposis
Neoplasms > Neoplastic Syndromes, Hereditary > Colorectal Neoplasms, Hereditary Nonpolyposis
Nutritional and Metabolic Diseases > Metabolic Diseases > DNA Repair-Deficiency Disorders > Colorectal Neoplasms, Hereditary Nonpolyposis

Preferred term

Colorectal Neoplasms, Hereditary Nonpolyposis  

Type

  • Topical Descriptor

Broader concept

Narrower concepts

Entry terms

  • Familial Nonpolyposis Colon Cancer
  • Hereditary Nonpolyposis Colorectal Neoplasms

Scope note

  • A group of autosomal-dominant inherited diseases in which COLON CANCER arises in discrete adenomas. Unlike FAMILIAL POLYPOSIS COLI with hundreds of polyps, hereditary nonpolyposis colorectal neoplasms occur much later, in the fourth and fifth decades. HNPCC has been associated with germline mutations in mismatch repair (MMR) genes. It has been subdivided into Lynch syndrome I or site-specific colonic cancer, and LYNCH SYNDROME II which includes extracolonic cancer.

History note

  • 87

In other languages

  • periytyvä ei-polypoottinen paksusuolisyöpä

    Finnish

  • hereditaarinen ei-polypoottinen paksusuolisyöpä
  • hereditary non-polypotic colorectal cancer
  • hereditäärinen ei-polypoottinen paksusuolisyöpä
  • HNPCC
  • Lynch
  • Lynchin oireyhtymä
  • Lynchin syndrooma
  • perinnöllinen ei-polypoottinen koolonkarsinooma
  • perinnöllinen ei-polypoottinen paksusuolen syöpä
  • perinnöllinen ei-polypoottinen paksusuolisyöpä
  • periytyvä ei-polypoottinen paksusuolen syöpä
  • Ärftliga icke-polyposa kolorektaltumörer

    Swedish

  • Lynchs syndrom
  • Ärftlig icke-polypos kolorektalcancer

URI

http://www.yso.fi/onto/mesh/D003123

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