Concept information
Preferred term
Complement C2
Type
-
Topical Descriptor
Broader concept
Narrower concepts
Entry terms
- C2 Complement
- Complement 2
- Complement, C2
- Complement Component 2
- Component 2, Complement
Scope note
- A component of the CLASSICAL COMPLEMENT PATHWAY. C2 is cleaved by activated COMPLEMENT C1S into COMPLEMENT C2B and COMPLEMENT C2A. C2a, the COOH-terminal fragment containing a SERINE PROTEASE, combines with COMPLEMENT C4B to form C4b2a (CLASSICAL PATHWAY C3 CONVERTASE) and subsequent C4b2a3b (CLASSICAL PATHWAY C5 CONVERTASE).
History note
- 2006 (1975)
In other languages
-
Finnish
-
C2
-
Swedish
URI
http://www.yso.fi/onto/mesh/D003175
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