Concept information
Preferred term
Complement C3b
Type
-
Topical Descriptor
Broader concept
Narrower concepts
Entry terms
- C3b Complement
- Complement 3b
- Complement, C3b
- Complement Component 3b
- Component 3b, Complement
Note
- /antag: consider COMPLEMENT C3B INACTIVATOR PROTEINS
Scope note
- The larger fragment generated from the cleavage of COMPLEMENT C3 by C3 CONVERTASE. It is a constituent of the ALTERNATIVE PATHWAY C3 CONVERTASE (C3bBb), and COMPLEMENT C5 CONVERTASES in both the classical (C4b2a3b) and the alternative (C3bBb3b) pathway. C3b participates in IMMUNE ADHERENCE REACTION and enhances PHAGOCYTOSIS. It can be inactivated (iC3b) or cleaved by various proteases to yield fragments such as COMPLEMENT C3C; COMPLEMENT C3D; C3e; C3f; and C3g.
History note
- 2006 (1978)
In other languages
-
Finnish
-
C3b
-
Swedish
URI
http://www.yso.fi/onto/mesh/D003179
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