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Concept information

Preferred term

Complement C7  

Type

  • Topical Descriptor

Entry terms

  • C7 Complement
  • Complement 7
  • Complement, C7
  • Complement Component 7
  • Component 7, Complement

Scope note

  • A 93-kDa serum glycoprotein encoded by C7 gene. It is a polypeptide chain with 28 disulfide bridges. In the formation of MEMBRANE ATTACK COMPLEX; C7 is the next component to bind the C5b-6 complex forming a trimolecular complex C5b-7 which is lipophilic, resembles an integral membrane protein, and serves as an anchor for the late complement components, C8 and C9.

History note

  • 2006 (1975)

In other languages

URI

http://www.yso.fi/onto/mesh/D003184

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