Concept information
Preferred term
Complement C8
Type
-
Topical Descriptor
Broader concept
Entry terms
- C8 Complement
- Complement 8
- Complement, C8
- Complement Component 8
- Component 8, Complement
Scope note
- A 150-kDa serum glycoprotein composed of three subunits with each encoded by a different gene (C8A; C8B; and C8G). This heterotrimer contains a disulfide-linked C8alpha-C8gamma heterodimer and a noncovalently associated C8beta chain. C8 is the next component to bind the C5-7 complex forming C5b-8 that binds COMPLEMENT C9 and acts as a catalyst in the polymerization of C9.
History note
- 2006 (1975)
In other languages
-
Finnish
-
C8
-
Swedish
URI
http://www.yso.fi/onto/mesh/D003185
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