Concept information
Preferred term
Complement C9
Type
-
Topical Descriptor
Broader concept
Entry terms
- C9 Complement
- Complement 9
- Complement, C9
- Complement Component 9
- Component 9, Complement
Scope note
- A 63-kDa serum glycoprotein encoded by gene C9. Monomeric C9 (mC9) binds the C5b-8 complex to form C5b-9 which catalyzes the polymerization of C9 forming C5b-p9 (MEMBRANE ATTACK COMPLEX) and transmembrane channels leading to lysis of the target cell. Patients with C9 deficiency suffer from recurrent bacterial infections.
History note
- 2006 (1975)
In other languages
-
Finnish
-
C9
-
Swedish
URI
http://www.yso.fi/onto/mesh/D003186
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