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Concept information

Preferred term

Cyclophosphamide  

Type

  • Topical Descriptor

Broader concept

Narrower concepts

Entry terms

  • (+,-)-2-(bis(2-Chloroethyl)amino)tetrahydro-2H-1,3,2-oxazaphosphorine 2-Oxide Monohydrate
  • B 518
  • B-518
  • B518
  • Cyclophosphamide Anhydrous
  • Cyclophosphamide Monohydrate
  • Cyclophosphamide, (R)-Isomer
  • Cyclophosphamide, (S)-Isomer
  • Cyclophosphane
  • Cytophosphan
  • Cytophosphane
  • Cytoxan
  • Endoxan
  • Neosar
  • NSC 26271
  • NSC-26271
  • NSC26271
  • Procytox
  • Sendoxan

Scope note

  • Precursor of an alkylating nitrogen mustard antineoplastic and immunosuppressive agent that must be activated in the LIVER to form the active aldophosphamide. It has been used in the treatment of LYMPHOMA and LEUKEMIA. Its side effect, ALOPECIA, has been used for defleecing sheep. Cyclophosphamide may also cause sterility, birth defects, mutations, and cancer.

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URI

http://www.yso.fi/onto/mesh/D003520

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