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... > Enzymes and Coenzymes > Enzymes > Lyases > Carbon-Oxygen Lyases > Hydro-Lyases > Cystathionine beta-Synthase

Preferred term

Cystathionine beta-Synthase  

Type

  • Topical Descriptor

Broader concept

Related concepts

Entry terms

  • beta Thionase
  • beta-Thionase
  • Cystathionine Synthetase
  • Serine Sulfhydrase
  • Sulfhydrase, Serine
  • Synthetase, Cystathionine

Note

  • /defic: consider also HOMOCYSTINURIA or HYPERHOMOCYSTEINEMIA

Scope note

  • A multifunctional pyridoxal phosphate enzyme. In the second stage of cysteine biosynthesis it catalyzes the reaction of homocysteine with serine to form cystathionine with the elimination of water. Deficiency of this enzyme leads to HYPERHOMOCYSTEINEMIA and HOMOCYSTINURIA. EC 4.2.1.22.

History note

  • 1991(1975)

In other languages

URI

http://www.yso.fi/onto/mesh/D003541

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