Concept information
Preferred term
Dapsone
Type
-
Topical Descriptor
Broader concept
Narrower concepts
Entry terms
- 4,4' Diaminophenyl Sulfone
- 4,4'-Diaminophenyl Sulfone
- DADPS
- Diaminodiphenylsulfone
- Diaphenylsulfone
- Sulfone, 4,4'-Diaminophenyl
- Sulfonyldianiline
Scope note
- A sulfone active against a wide range of bacteria but mainly employed for its actions against MYCOBACTERIUM LEPRAE. Its mechanism of action is probably similar to that of the SULFONAMIDES which involves inhibition of folic acid synthesis in susceptible organisms. It is also used with PYRIMETHAMINE in the treatment of malaria. (From Martindale, The Extra Pharmacopoeia, 30th ed, p157-8)
URI
http://www.yso.fi/onto/mesh/D003622
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