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... > Organic Chemicals > Hydrocarbons > Hydrocarbons, Cyclic > Hydrocarbons, Aromatic > Polycyclic Aromatic Hydrocarbons > Phenanthrenes > Morphinans > Dextromethorphan
Polycyclic Compounds > Polycyclic Aromatic Hydrocarbons > Phenanthrenes > Morphinans > Dextromethorphan
Heterocyclic Compounds > Heterocyclic Compounds, Fused-Ring > Heterocyclic Compounds, 4 or More Rings > Morphinans > Dextromethorphan
Heterocyclic Compounds > Alkaloids > Opiate Alkaloids > Morphinans > Dextromethorphan
Heterocyclic Compounds > Heterocyclic Compounds, Bridged-Ring > Morphinans > Dextromethorphan

Preferred term

Dextromethorphan  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • d-Methorphan

Scope note

  • Methyl analog of DEXTRORPHAN that shows high affinity binding to several regions of the brain, including the medullary cough center. This compound is an NMDA receptor antagonist (RECEPTORS, N-METHYL-D-ASPARTATE) and acts as a non-competitive channel blocker. It is one of the widely used ANTITUSSIVES, and is also used to study the involvement of glutamate receptors in neurotoxicity.

History note

  • 91(72); was see under LEVORPHANOL 1972-90

In other languages

URI

http://www.yso.fi/onto/mesh/D003915

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