Concept information
Preferred term
Dianhydrogalactitol
Type
-
Topical Descriptor
Broader concept
Entry terms
- 1,2,5,6-Dianhydrogalactitol
- 1,2-5,6-Dianhydrogalactitol
- Dianhydrodulcitol
- Diepoxydulcitol
- Diepoxygalactitol
Scope note
- One of the cytotoxic dihalohexitols that alkylates and cross-links DNA via an epoxide group during all phases of the cell cycle, resulting in a disruption of DNA function and cell cycle arrest. It has antineoplastic activity and also causes bone marrow toxicity.
History note
- 91(79); was see under SUGAR ALCOHOLS 1979-90
In other languages
-
Finnish
-
Swedish
URI
http://www.yso.fi/onto/mesh/D003961
{{label}}
{{#each values }} {{! loop through ConceptPropertyValue objects }}
{{#if prefLabel }}
{{/if}}
{{/each}}
{{#if notation }}{{ notation }} {{/if}}{{ prefLabel }}
{{#ifDifferentLabelLang lang }} ({{ lang }}){{/ifDifferentLabelLang}}
{{#if vocabName }}
{{ vocabName }}
{{/if}}