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Biological Factors > Toxins, Biological > Bacterial Toxins > Diphtheria Toxin
... > Enzymes and Coenzymes > Enzymes > Transferases > Glycosyltransferases > Pentosyltransferases > ADP Ribose Transferases > Diphtheria Toxin

Preferred term

Diphtheria Toxin  

Type

  • Topical Descriptor

Broader concept

Related concepts

Entry terms

  • Corynebacterium Diphtheriae Toxin
  • Toxin, Corynebacterium Diphtheriae

Note

  • /antag permitted but consider also DIPHTHERIA ANTITOXIN

Scope note

  • An ADP-ribosylating polypeptide produced by CORYNEBACTERIUM DIPHTHERIAE that causes the signs and symptoms of DIPHTHERIA. It can be broken into two unequal domains: the smaller, catalytic A domain is the lethal moiety and contains MONO(ADP-RIBOSE) TRANSFERASES which transfers ADP RIBOSE to PEPTIDE ELONGATION FACTOR 2 thereby inhibiting protein synthesis; and the larger B domain that is needed for entry into cells.

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URI

http://www.yso.fi/onto/mesh/D004167

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