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Inorganic Chemicals > Sulfur Compounds > Thiocarbamates > Ditiocarb > Disulfiram
Organic Chemicals > Sulfur Compounds > Thiocarbamates > Ditiocarb > Disulfiram
... > Organic Chemicals > Carboxylic Acids > Acids, Acyclic > Carbamates > Thiocarbamates > Ditiocarb > Disulfiram
... > Inorganic Chemicals > Electrolytes > Ions > Anions > Sulfides > Disulfides > Disulfiram
... > Inorganic Chemicals > Sulfur Compounds > Hydrogen Sulfide > Sulfides > Disulfides > Disulfiram
... > Organic Chemicals > Sulfur Compounds > Hydrogen Sulfide > Sulfides > Disulfides > Disulfiram
... > Inorganic Chemicals > Gases > Hydrogen Sulfide > Sulfides > Disulfides > Disulfiram
... > Inorganic Chemicals > Acids > Acids, Noncarboxylic > Hydrogen Sulfide > Sulfides > Disulfides > Disulfiram

Preferred term

Disulfiram  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Bis(diethylthiocarbamoyl) Disulfide
  • Disulfide, Tetraethylthiuram
  • Tetraethylthioperoxydicarbonic Diamide, ((H2N)C(S))2S2
  • Tetraethylthiuram Disulfide

Scope note

  • A carbamate derivative used as an alcohol deterrent. It is a relatively nontoxic substance when administered alone, but markedly alters the intermediary metabolism of alcohol. When alcohol is ingested after administration of disulfiram, blood acetaldehyde concentrations are increased, followed by flushing, systemic vasodilation, respiratory difficulties, nausea, hypotension, and other symptoms (acetaldehyde syndrome). It acts by inhibiting aldehyde dehydrogenase.

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URI

http://www.yso.fi/onto/mesh/D004221

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