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... > Enzymes and Coenzymes > Enzymes > Transferases > Phosphotransferases > Nucleotidyltransferases > DNA Nucleotidyltransferases > DNA-Directed DNA Polymerase > DNA Polymerase I

Preferred term

DNA Polymerase I  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • DNA Dependent DNA Polymerase I
  • DNA-Dependent DNA Polymerase I
  • DNA Pol I
  • DNA Polymerase alpha
  • Klenow Fragment
  • Polymerase alpha, DNA

Scope note

  • A DNA-dependent DNA polymerase characterized in prokaryotes and may be present in higher organisms. It has both 3'-5' and 5'-3' exonuclease activity, but cannot use native double-stranded DNA as template-primer. It is not inhibited by sulfhydryl reagents and is active in both DNA synthesis and repair.

History note

  • 84(77); for DNA POLYMERASE ALPHA use DNA POLYMERASE II 1982-97

In other languages

URI

http://www.yso.fi/onto/mesh/D004256

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