Skip to main content

Medical Subject Headings

Search from vocabulary

Content language

Concept information

... > Enzymes and Coenzymes > Enzymes > Transferases > Phosphotransferases > Nucleotidyltransferases > DNA Nucleotidyltransferases > DNA-Directed DNA Polymerase > DNA Polymerase II

Preferred term

DNA Polymerase II  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • DNA Dependent DNA Polymerase II
  • DNA-Dependent DNA Polymerase II
  • DNA Pol II
  • DNA Polymerase epsilon

Scope note

  • A DNA-dependent DNA polymerase characterized in E. coli and other lower organisms. It may be present in higher organisms and has an intrinsic molecular activity only 5% of that of DNA Polymerase I. This polymerase has 3'-5' exonuclease activity, is effective only on duplex DNA with gaps or single-strand ends of less than 100 nucleotides as template, and is inhibited by sulfhydryl reagents.

History note

  • 84(77); for DNA POLYMERASE EPSILON use DNA POLYMERASE II (NM) 1994-97

In other languages

URI

http://www.yso.fi/onto/mesh/D004257

Download this concept:

RDF/XML TURTLE JSON-LD Created 4/21/76, last modified 6/25/24