Skip to main content

Medical Subject Headings

Search from vocabulary

Content language

Concept information

Nucleic Acids, Nucleotides, and Nucleosides > Nucleic Acids > DNA > DNA, Circular
Genetic Phenomena > Genetic Structures > Nucleic Acid Conformation > DNA, Circular
... > Chemical Phenomena > Biochemical Phenomena > Molecular Structure > Molecular Conformation > Nucleic Acid Conformation > DNA, Circular

Preferred term

DNA, Circular  

Type

  • Topical Descriptor

Broader concept

Narrower concepts

Entry terms

  • Circular DNA

Note

  • IM; /drug eff /ultrastruct permitted

Scope note

  • Any of the covalently closed DNA molecules found in bacteria, many viruses, mitochondria, plastids, and plasmids. Small, polydisperse circular DNA's have also been observed in a number of eukaryotic organisms and are suggested to have homology with chromosomal DNA and the capacity to be inserted into, and excised from, chromosomal DNA. It is a fragment of DNA formed by a process of looping out and deletion, containing a constant region of the mu heavy chain and the 3'-part of the mu switch region. Circular DNA is a normal product of rearrangement among gene segments encoding the variable regions of immunoglobulin light and heavy chains, as well as the T-cell receptor. (Riger et al., Glossary of Genetics, 5th ed & Segen, Dictionary of Modern Medicine, 1992)

History note

  • 74(73)

In other languages

URI

http://www.yso.fi/onto/mesh/D004270

Download this concept:

RDF/XML TURTLE JSON-LD Created 1/1/99, last modified 6/22/15