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Concept information

Preferred term

DNA, Satellite  

Type

  • Topical Descriptor

Entry terms

  • DNAs, Satellite
  • Satellite DNA
  • Satellite DNAs

Scope note

  • Highly repetitive DNA sequences found in HETEROCHROMATIN, mainly near centromeres. They are composed of simple sequences (very short) (see MINISATELLITE REPEATS) repeated in tandem many times to form large blocks of sequence. Additionally, following the accumulation of mutations, these blocks of repeats have been repeated in tandem themselves. The degree of repetition is on the order of 1000 to 10 million at each locus. Loci are few, usually one or two per chromosome. They were called satellites since in density gradients, they often sediment as distinct, satellite bands separate from the bulk of genomic DNA owing to a distinct BASE COMPOSITION.

History note

  • 80(75); was see under DNA 1975-79

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URI

http://www.yso.fi/onto/mesh/D004276

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