Skip to main content

Medical Subject Headings

Search from vocabulary

Content language

Concept information

Genetic Phenomena > Gene Expression Regulation > Epigenesis, Genetic > Dosage Compensation, Genetic

Preferred term

Dosage Compensation, Genetic  

Type

  • Topical Descriptor

Broader concept

Narrower concepts

Entry terms

  • Compensation, Dosage (Genetics)
  • Compensation, Gene Dosage
  • Dosage Compensation, Gene
  • Dosage Compensation (Genetics)
  • Gene Dosage Compensation
  • Gene Dosage Compensations

Note

  • do not confuse with GENE DOSAGE

Scope note

  • Genetic mechanisms that allow GENES to be expressed at a similar level irrespective of their GENE DOSAGE. This term is usually used in discussing genes that lie on the SEX CHROMOSOMES. Because the sex chromosomes are only partially homologous, there is a different copy number, i.e., dosage, of these genes in males vs. females. In DROSOPHILA, dosage compensation is accomplished by hypertranscription of genes located on the X CHROMOSOME. In mammals, dosage compensation of X chromosome genes is accomplished by random X CHROMOSOME INACTIVATION of one of the two X chromosomes in the female.

History note

  • 2006 (1982)

In other languages

URI

http://www.yso.fi/onto/mesh/D004303

Download this concept:

RDF/XML TURTLE JSON-LD Created 2/23/81, last modified 6/17/16