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Concept information

Cardiovascular Diseases > Heart Diseases > Cardiomyopathies > Endocardial Fibroelastosis

Preferred term

Endocardial Fibroelastosis  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Endomyocardial Fibroelastosis

Scope note

  • A condition characterized by the thickening of ENDOCARDIUM due to proliferation of fibrous and elastic tissue, usually in the left ventricle leading to impaired cardiac function (CARDIOMYOPATHY, RESTRICTIVE). It is most commonly seen in young children and rarely in adults. It is often associated with congenital heart anomalies (HEART DEFECTS CONGENITAL;) INFECTION; or gene mutation. Defects in the tafazzin protein, encoded by TAZ gene, result in a form of autosomal dominant familial endocardial fibroelastosis.

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URI

http://www.yso.fi/onto/mesh/D004695

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