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Concept information

Preferred term

Enzyme-Linked Immunosorbent Assay  

Type

  • Topical Descriptor

Entry terms

  • ELISA

Note

  • NIM; IMMUNOSORBENTS is also available

Scope note

  • An immunoassay utilizing an antibody labeled with an enzyme marker such as horseradish peroxidase. While either the enzyme or the antibody is bound to an immunosorbent substrate, they both retain their biologic activity; the change in enzyme activity as a result of the enzyme-antibody-antigen reaction is proportional to the concentration of the antigen and can be measured spectrophotometrically or with the naked eye. Many variations of the method have been developed.

History note

  • 86(77); was see under IMMUNOENZYME TECHNIQUES 1977-85

In other languages

URI

http://www.yso.fi/onto/mesh/D004797

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