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Amino Acids, Peptides, and Proteins > Proteins > Mitochondrial Proteins > Ferrochelatase
... > Amino Acids, Peptides, and Proteins > Proteins > Carrier Proteins > Iron-Binding Proteins > Nonheme Iron Proteins > Iron-Sulfur Proteins > Ferrochelatase
... > Amino Acids, Peptides, and Proteins > Proteins > Metalloproteins > Iron-Binding Proteins > Nonheme Iron Proteins > Iron-Sulfur Proteins > Ferrochelatase
Enzymes and Coenzymes > Enzymes > Lyases > Ferrochelatase

Preferred term

Ferrochelatase  

Type

  • Topical Descriptor

Broader concept

Related concepts

Entry terms

  • Chelatase, Porphyrin-Metal
  • Ferro-Lyase, Protoheme
  • Heme Synthetase
  • Porphyrin Metal Chelatase
  • Porphyrin-Metal Chelatase
  • Protoheme Ferro Lyase
  • Protoheme Ferro-Lyase
  • Synthetase, Heme

Scope note

  • A mitochondrial enzyme found in a wide variety of cells and tissues. It is the final enzyme in the 8-enzyme biosynthetic pathway of HEME. Ferrochelatase catalyzes ferrous insertion into protoporphyrin IX to form protoheme or heme. Deficiency in this enzyme results in ERYTHROPOIETIC PROTOPORPHYRIA.

History note

  • 1991(1977); use LYASES 1977-1990

In other languages

URI

http://www.yso.fi/onto/mesh/D005294

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