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Biological Factors > Blood Coagulation Factors > Fibrinogen
Amino Acids, Peptides, and Proteins > Proteins > Blood Proteins > Blood Coagulation Factors > Fibrinogen
Amino Acids, Peptides, and Proteins > Proteins > Protein Precursors > Fibrinogen
Amino Acids, Peptides, and Proteins > Proteins > Blood Proteins > Acute-Phase Proteins > Fibrinogen

Preferred term

Fibrinogen  

Type

  • Topical Descriptor

Broader concept

Narrower concepts

Related concepts

Entry terms

  • Blood Coagulation Factor I
  • Coagulation Factor I
  • Factor I
  • Factor I, Coagulation

Note

  • a blood coag factor: do not confuse entry term FACTOR I with COMPLEMENT FACTOR I

Scope note

  • Plasma glycoprotein clotted by thrombin, composed of a dimer of three non-identical pairs of polypeptide chains (alpha, beta, gamma) held together by disulfide bonds. Fibrinogen clotting is a sol-gel change involving complex molecular arrangements: whereas fibrinogen is cleaved by thrombin to form polypeptides A and B, the proteolytic action of other enzymes yields different fibrinogen degradation products.

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URI

http://www.yso.fi/onto/mesh/D005340

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