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Enzymes and Coenzymes > Enzymes > Ligases > Carbon-Nitrogen Ligases > Formate-Tetrahydrofolate Ligase

Preferred term

Formate-Tetrahydrofolate Ligase  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Formylase, Tetrahydrofolate
  • Formyltetrahydrofolate Synthetase
  • Synthetase, Formyltetrahydrofolate
  • Tetrahydrofolate Formylase

Scope note

  • A carbon-nitrogen ligase that catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate in the presence of ATP. In higher eukaryotes the enzyme also contains METHYLENETETRAHYDROFOLATE DEHYDROGENASE (NADP+) and METHENYLTETRAHYDROFOLATE CYCLOHYDROLASE activity.

History note

  • 98(75)

URI

http://www.yso.fi/onto/mesh/D005574

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RDF/XML TURTLE JSON-LD Created 11/19/74, last modified 7/10/09