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Heterocyclic Compounds > Heterocyclic Compounds, 1-Ring > Pyridines > Picolinic Acids > Fusaric Acid
Heterocyclic Compounds > Acids, Heterocyclic > Picolinic Acids > Fusaric Acid

Preferred term

Fusaric Acid  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • 5 Butyl 2 pyridinedicarboxylic Acid
  • 5-Butyl-2-pyridinedicarboxylic Acid
  • Acid, 5-Butyl-2-pyridinedicarboxylic

Note

  • /biosyn permitted if by organism

Scope note

  • A picolinic acid derivative isolated from various Fusarium species. It has been proposed for a variety of therapeutic applications but is primarily used as a research tool. Its mechanisms of action are poorly understood. It probably inhibits DOPAMINE BETA-HYDROXYLASE, the enzyme that converts dopamine to norepinephrine. It may also have other actions, including the inhibition of cell proliferation and DNA synthesis.

History note

  • 91(75); was see under PICOLINIC ACIDS 1975-90

In other languages

URI

http://www.yso.fi/onto/mesh/D005669

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