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Concept information

Preferred term

Genes, Homeobox  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Gene, Homeo Box
  • Gene, Homeotic
  • Gene, Hox
  • Genes, Homeo Box
  • Genes, Homeotic
  • Genes, Hox
  • Homeo Box Gene
  • Homeo Box Genes
  • Homeotic Gene
  • Homeotic Genes
  • Hox Gene
  • Hox Genes

Scope note

  • Genes that encode highly conserved TRANSCRIPTION FACTORS that control positional identity of cells (BODY PATTERNING) and MORPHOGENESIS throughout development. Their sequences contain a 180 nucleotide sequence designated the homeobox, so called because mutations of these genes often results in homeotic transformations, in which one body structure replaces another. The proteins encoded by homeobox genes are called HOMEODOMAIN PROTEINS.

History note

  • 95; was GENES, HOMEO BOX 1987-94

In other languages

URI

http://www.yso.fi/onto/mesh/D005801

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