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Concept information

Preferred term

Globosides  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Cytolipins

Note

  • /biosyn /physiol permitted

Scope note

  • Glycosphingolipids containing N-acetylglucosamine (paragloboside) or N-acetylgalactosamine (globoside). Globoside is the P antigen on erythrocytes and paragloboside is an intermediate in the biosynthesis of erythrocyte blood group ABH and P 1 glycosphingolipid antigens. The accumulation of globoside in tissue, due to a defect in hexosaminidases A and B, is the cause of Sandhoff disease.

History note

  • 91(79); was see under GLYCOSPHINGOLIPIDS 1979-90

In other languages

URI

http://www.yso.fi/onto/mesh/D005915

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