Concept information
Preferred term
Globosides
Type
-
Topical Descriptor
Broader concept
Entry terms
- Cytolipins
Note
- /biosyn /physiol permitted
Scope note
- Glycosphingolipids containing N-acetylglucosamine (paragloboside) or N-acetylgalactosamine (globoside). Globoside is the P antigen on erythrocytes and paragloboside is an intermediate in the biosynthesis of erythrocyte blood group ABH and P 1 glycosphingolipid antigens. The accumulation of globoside in tissue, due to a defect in hexosaminidases A and B, is the cause of Sandhoff disease.
History note
- 91(79); was see under GLYCOSPHINGOLIPIDS 1979-90
In other languages
-
Finnish
-
globosidi
-
Swedish
URI
http://www.yso.fi/onto/mesh/D005915
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