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... > Enzymes and Coenzymes > Enzymes > Lyases > Carbon-Carbon Lyases > Carboxy-Lyases > Glutamate Decarboxylase

Preferred term

Glutamate Decarboxylase  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Acid Decarboxylase, Glutamic
  • Carboxy-Lyase, Glutamate
  • Decarboxylase, Glutamic Acid
  • Glutamate Carboxy Lyase
  • Glutamate Carboxy-Lyase
  • Glutamic Acid Decarboxylase

Scope note

  • A pyridoxal-phosphate protein that catalyzes the alpha-decarboxylation of L-glutamic acid to form gamma-aminobutyric acid and carbon dioxide. The enzyme is found in bacteria and in invertebrate and vertebrate nervous systems. It is the rate-limiting enzyme in determining GAMMA-AMINOBUTYRIC ACID levels in normal nervous tissues. The brain enzyme also acts on L-cysteate, L-cysteine sulfinate, and L-aspartate. EC 4.1.1.15.

History note

  • 84(75); was see under CARBOXY-LYASES 1975-83

In other languages

URI

http://www.yso.fi/onto/mesh/D005968

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