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Concept information

Preferred term

Glycogen Debranching Enzyme System  

Type

  • Topical Descriptor

Entry terms

  • Transfer Glucosidase
  • Transfer-Glucosidase

Note

  • /defic: consider also GLYCOGEN STORAGE DISEASE TYPE III

Scope note

  • 1,4-alpha-D-Glucan-1,4-alpha-D-glucan 4-alpha-D-glucosyltransferase/dextrin 6 alpha-D-glucanohydrolase. An enzyme system having both 4-alpha-glucanotransferase (EC 2.4.1.25) and amylo-1,6-glucosidase (EC 3.2.1.33) activities. As a transferase it transfers a segment of a 1,4-alpha-D-glucan to a new 4-position in an acceptor, which may be glucose or another 1,4-alpha-D-glucan. As a glucosidase it catalyzes the endohydrolysis of 1,6-alpha-D-glucoside linkages at points of branching in chains of 1,4-linked alpha-D-glucose residues. Amylo-1,6-glucosidase activity is deficient in glycogen storage disease type III.

History note

  • 89(76); was GLYCOGEN DEBRANCHING ENZYME see under GLUCOSYLTRANSFERASES 1976-88

URI

http://www.yso.fi/onto/mesh/D006004

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