Concept information
Preferred term
GTP Cyclohydrolase
Type
-
Topical Descriptor
Broader concept
Entry terms
- 7,8 Dihydroneopterintriphosphate Synthetase
- 7,8-Dihydroneopterintriphosphate Synthetase
- 8-Formylhydrolase, GTP
- Dihydrolase, GTP
- GTP 8 Formylhydrolase
- GTP 8-Formylhydrolase
- GTP Dihydrolase
- GTP Ring Opening Enzyme
- GTP Ring-Opening Enzyme
- Ring-Opening Enzyme, GTP
- Synthetase, 7,8-Dihydroneopterintriphosphate
Scope note
- (GTP cyclohydrolase I) or GTP 7,8-8,9-dihydrolase (pyrophosphate-forming) (GTP cyclohydrolase II). An enzyme group that hydrolyzes the imidazole ring of GTP, releasing carbon-8 as formate. Two C-N bonds are hydrolyzed and the pentase unit is isomerized. This is the first step in the synthesis of folic acid from GTP. EC 3.5.4.16 (GTP cyclohydrolase I) and EC 3.5.4.25 (GTP cyclohydrolase II).
History note
- 91(75); was see under AMINOHYDROLASES 1975-90
In other languages
-
Finnish
-
Swedish
URI
http://www.yso.fi/onto/mesh/D006136
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