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Concept information

Preferred term

Guanylyl Imidodiphosphate  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • GMP-P(NH)P
  • GMP-PNP
  • Gpp(NH)p
  • Guanosine 5'-(Beta,Gamma-Imido)Triphosphate
  • Guanyl 5' Imidodiphosphate
  • Guanyl-5'-Imidodiphosphate
  • P(NH)PPG

Scope note

  • A non-hydrolyzable analog of GTP, in which the oxygen atom bridging the beta to the gamma phosphate is replaced by a nitrogen atom. It binds tightly to G-protein in the presence of Mg2+. The nucleotide is a potent stimulator of ADENYLYL CYCLASES.

History note

  • 91(78); was see under GUANOSINE TRIPHOSPHATE 1978-90

In other languages

URI

http://www.yso.fi/onto/mesh/D006165

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