Concept information
Preferred term
Histone Deacetylases
Type
-
Topical Descriptor
Broader concept
Narrower concepts
Entry terms
- Deacetylase, Histone
- HDAC Proteins
- Histone Deacetylase
Scope note
- Deacetylases that remove N-acetyl groups from amino side chains of the amino acids of HISTONES. The enzyme family can be divided into at least three structurally-defined subclasses. Class I and class II deacetylases utilize a zinc-dependent mechanism. The sirtuin histone deacetylases belong to class III and are NAD-dependent enzymes.
History note
- 2003; use AMIDOHYDROLASES 1975-1990
In other languages
-
Finnish
-
histonideasetylaasi
-
Swedish
URI
http://www.yso.fi/onto/mesh/D006655
{{label}}
{{#each values }} {{! loop through ConceptPropertyValue objects }}
{{#if prefLabel }}
{{/if}}
{{/each}}
{{#if notation }}{{ notation }} {{/if}}{{ prefLabel }}
{{#ifDifferentLabelLang lang }} ({{ lang }}){{/ifDifferentLabelLang}}
{{#if vocabName }}
{{ vocabName }}
{{/if}}