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Biological Factors > Toxins, Biological > Hypoglycins
Polycyclic Compounds > Macrocyclic Compounds > Cycloparaffins > Cyclopropanes > Hypoglycins
... > Organic Chemicals > Hydrocarbons > Hydrocarbons, Cyclic > Hydrocarbons, Alicyclic > Cycloparaffins > Cyclopropanes > Hypoglycins

Preferred term

Hypoglycins  

Type

  • Topical Descriptor

Broader concept

Note

  • Jamaican vomiting sickness : coordinate HYPOGLYCINS /pois (IM) with PLANT POISONING (IM)

Scope note

  • Methylene cyclopropyl alanine and congeners isolated from the unripe edible fruit of the AKEE plant (BLIGHIA SAPIDA). Hypoglycin B is the gamma-glutamyl congener of hypoglycin A. They are very toxic and teratogenic, causing a syndrome called Jamaican vomiting sickness that includes a fall in blood glucose due to the interference of FATTY ACIDS and LEUCINE metabolism which leads to VOMITING, liver damage, CONVULSIONS and DEATH.

History note

  • 91(77); was see under CYCLOPROPANES 1977-90

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URI

http://www.yso.fi/onto/mesh/D007005

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