Concept information
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Immunoglobulins
Immunoglobulin Fragments
Immunoglobulin Fab Fragments
Immunoglobulin Variable Region
...
Immunoglobulins
Immunoglobulin Fragments
Immunoglobulin Fab Fragments
Immunoglobulin Variable Region
Preferred term
Immunoglobulin Joining Region
Type
-
Topical Descriptor
Broader concept
Entry terms
- Ig Joining Region
- Joining Region, Ig
Scope note
- A segment of the immunoglobulin heavy chains, encoded by the IMMUNOGLOBULIN HEAVY CHAIN GENES in the J segment where, during the maturation of B-LYMPHOCYTES; the gene segment for the variable region upstream is joined to a constant region gene segment downstream. The exact position of joining of the two gene segments is variable and contributes to ANTIBODY DIVERSITY. It is distinguished from the IMMUNOGLOBULIN J CHAINS; a separate polypeptide that serves as a linkage piece in polymeric IGA or IGM.
History note
- 88
In other languages
-
Finnish
-
immunoglobuliinin liitosvyöhyke
-
Swedish
URI
http://www.yso.fi/onto/mesh/D007133
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