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Concept information

Preferred term

Immunoglobulin Joining Region  

Type

  • Topical Descriptor

Entry terms

  • Ig Joining Region
  • Joining Region, Ig

Scope note

  • A segment of the immunoglobulin heavy chains, encoded by the IMMUNOGLOBULIN HEAVY CHAIN GENES in the J segment where, during the maturation of B-LYMPHOCYTES; the gene segment for the variable region upstream is joined to a constant region gene segment downstream. The exact position of joining of the two gene segments is variable and contributes to ANTIBODY DIVERSITY. It is distinguished from the IMMUNOGLOBULIN J CHAINS; a separate polypeptide that serves as a linkage piece in polymeric IGA or IGM.

History note

  • 88

In other languages

URI

http://www.yso.fi/onto/mesh/D007133

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