Concept information
Preferred term
Immunoglobulin Variable Region
Type
-
Topical Descriptor
Broader concept
Narrower concepts
Entry terms
- Ig Variable Region
- Ig Variable Regions
- Immunoglobulin V
- Variable Region, Ig
- Variable Region, Immunoglobulin
- Variable Regions, Ig
Scope note
- That region of the immunoglobulin molecule that varies in its amino acid sequence and composition, and comprises the binding site for a specific antigen. It is located at the N-terminus of the Fab fragment of the immunoglobulin. It includes hypervariable regions (COMPLEMENTARITY DETERMINING REGIONS) and framework regions.
History note
- 84(77); was see under BINDING SITES, ANTIBODY 1977-83
In other languages
-
Finnish
-
immunoglobuliinin muuttuva vyöhyke
-
Swedish
URI
http://www.yso.fi/onto/mesh/D007135
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