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Concept information

Preferred term

Immunoglobulin Variable Region  

Type

  • Topical Descriptor

Entry terms

  • Ig Variable Region
  • Ig Variable Regions
  • Immunoglobulin V
  • Variable Region, Ig
  • Variable Region, Immunoglobulin
  • Variable Regions, Ig

Scope note

  • That region of the immunoglobulin molecule that varies in its amino acid sequence and composition, and comprises the binding site for a specific antigen. It is located at the N-terminus of the Fab fragment of the immunoglobulin. It includes hypervariable regions (COMPLEMENTARITY DETERMINING REGIONS) and framework regions.

History note

  • 84(77); was see under BINDING SITES, ANTIBODY 1977-83

In other languages

URI

http://www.yso.fi/onto/mesh/D007135

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