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Amino Acids, Peptides, and Proteins > Proteins > Blood Proteins > Serum Globulins > Immunoglobulins
Amino Acids, Peptides, and Proteins > Proteins > Globulins > Serum Globulins > Immunoglobulins
Amino Acids, Peptides, and Proteins > Proteins > Blood Proteins > Immunoproteins > Immunoglobulins

Preferred term

Immunoglobulins  

Type

  • Topical Descriptor

Broader concept

Narrower concepts

Related concepts

Entry terms

  • Globulin, Immune
  • Globulins, Immune
  • Immune Globulin
  • Immune Globulins
  • Immunoglobulin

Note

  • general: prefer specifics; /admin: consider also IMMUNOGLOBULINS, INTRAVENOUS; /defic permitted but consider also IMMUNOLOGIC DEFICIENCY SYNDROMES ; /ther use: consider also IMMUNOGLOBULIN THERAPY see IMMUNIZATION, PASSIVE; allotypes = IMMUNOGLOBULIN ALLOTYPES or specifics

Scope note

  • Multi-subunit proteins which function in IMMUNITY. They are produced by B LYMPHOCYTES from the IMMUNOGLOBULIN GENES. They are comprised of two heavy (IMMUNOGLOBULIN HEAVY CHAINS) and two light chains (IMMUNOGLOBULIN LIGHT CHAINS) with additional ancillary polypeptide chains depending on their isoforms. The variety of isoforms include monomeric or polymeric forms, and transmembrane forms (B-CELL ANTIGEN RECEPTORS) or secreted forms (ANTIBODIES). They are divided by the amino acid sequence of their heavy chains into five classes (IMMUNOGLOBULIN A; IMMUNOGLOBULIN D; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M) and various subclasses.

History note

  • 72(70); IMMUNE SERUM GLOBULIN was heading 1965; GLOBULINS, IMMUNE & IMMUNE GLOBULINS were see IMMUNOGLOBULINS, INTRAVENOUS 1992-93

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URI

http://www.yso.fi/onto/mesh/D007136

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