Concept information
Preferred term
Immunoglobulin Fc Fragments
Type
-
Topical Descriptor
Broader concept
Narrower concepts
Entry terms
- Fc Fragment
- Fc Fragment, Immunoglobulin
- Fc Fragment Immunoglobulins
- Fc Fragments
- Fc Fragments, Ig
- Fc Immunoglobulin
- Fc Immunoglobulins
- Fragment, Fc
- Fragment Immunoglobulins, Fc
- Fragments, Ig Fc
- Ig Fc Fragments
- Immunoglobulin, Fc
- Immunoglobulin Fc Fragment
- Immunoglobulins, Fc
- Immunoglobulins, Fc Fragment
Scope note
- Crystallizable fragments composed of the carboxy-terminal halves of both IMMUNOGLOBULIN HEAVY CHAINS linked to each other by disulfide bonds. Fc fragments contain the carboxy-terminal parts of the heavy chain constant regions that are responsible for the effector functions of an immunoglobulin (COMPLEMENT fixation, binding to the cell membrane via FC RECEPTORS, and placental transport). This fragment can be obtained by digestion of immunoglobulins with the proteolytic enzyme PAPAIN.
History note
- 2006 (1973)
In other languages
-
Finnish
-
Fc-osa
-
immunoglobuliinien Fc-osat
-
immunoglobuliinin Fc-osa
-
Swedish
-
Immunoglobuliner, Fc
URI
http://www.yso.fi/onto/mesh/D007141
{{label}}
{{#each values }} {{! loop through ConceptPropertyValue objects }}
{{#if prefLabel }}
{{/if}}
{{/each}}
{{#if notation }}{{ notation }} {{/if}}{{ prefLabel }}
{{#ifDifferentLabelLang lang }} ({{ lang }}){{/ifDifferentLabelLang}}
{{#if vocabName }}
{{ vocabName }}
{{/if}}