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Concept information

Preferred term

Immunoglobulin gamma-Chains  

Type

  • Topical Descriptor

Narrower concepts

Entry terms

  • gamma-Chain, Immunoglobulin
  • gamma Chain Immunoglobulins
  • gamma-Chain Immunoglobulins
  • gamma Immunoglobulin Heavy Chain
  • gamma Immunoglobulin Heavy Chains
  • Immunoglobulin gamma Chain
  • Immunoglobulin gamma-Chain
  • Immunoglobulins, gamma Chain
  • Immunoglobulins, gamma-Chain

Note

  • gammopathy: coordinate IMMUNOGLOBULIN GAMMA-CHAINS (IM) with PARAPROTEINEMIAS (IM) but consider also HYPERGAMMAGLOBULINEMIA (IM) or HEAVY CHAIN DISEASE (IM), follow text; DF: IG GAMMA CHAIN

Scope note

  • Heavy chains of IMMUNOGLOBULIN G having a molecular weight of approximately 51 kDa. They contain about 450 amino acid residues arranged in four domains and an oligosaccharide component covalently bound to the Fc fragment constant region. The gamma heavy chain subclasses (for example, gamma 1, gamma 2a, and gamma 2b) of the IMMUNOGLOBULIN G isotype subclasses (IgG1, IgG2A, and IgG2B) resemble each other more closely than the heavy chains of the other IMMUNOGLOBULIN ISOTYPES.

History note

  • 2006 (1976)

In other languages

URI

http://www.yso.fi/onto/mesh/D007142

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