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Immune System Phenomena > Antigen-Antibody Reactions > Immunologic Capping
Cell Physiological Phenomena > Receptor Aggregation > Immunologic Capping

Preferred term

Immunologic Capping  

Type

  • Topical Descriptor

Broader concept

Related concepts

Entry terms

  • Capping, Immunologic
  • Capping, Immunological
  • Immunological Capping

Note

  • may appear in the literature as "capping of lymphocytes" or "leukocyte capping"; do not confuse with RECEPTOR CAPPING

Scope note

  • An energy dependent process following the crosslinking of B CELL ANTIGEN RECEPTORS by multivalent ligands (bivalent anti-antibodies, LECTINS or ANTIGENS), on the B-cell surface. The crosslinked ligand-antigen receptor complexes collect in patches which flow to and aggregate at one pole of the cell to form a large mass - the cap. The caps may then be endocytosed or shed into the environment.

History note

  • 78

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URI

http://www.yso.fi/onto/mesh/D007152

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