Skip to main content

Medical Subject Headings

Search from vocabulary

Content language

Concept information

Amino Acids, Peptides, and Proteins > Proteins > Protein Precursors > Proinsulin > Insulin
... > Chemical Actions and Uses > Pharmacologic Actions > Physiological Effects of Drugs > Hormones, Hormone Substitutes, and Hormone Antagonists > Hormones > Peptide Hormones > Pancreatic Hormones > Insulins > Proinsulin > Insulin
... > Amino Acids, Peptides, and Proteins > Peptides > Peptide Hormones > Pancreatic Hormones > Insulins > Proinsulin > Insulin

Preferred term

Insulin  

Type

  • Topical Descriptor

Broader concept

Narrower concepts

Related concepts

Entry terms

  • Insulin, Regular
  • Insulin, Soluble
  • Regular Insulin
  • Soluble Insulin

Note

  • /blood: consider also HYPERINSULINEMIA (excessively high blood insulin levels) but do not confuse with HYPERINSULINISM (excessive secretion of insulin by pancreas); /immunology: consider also INSULIN ANTIBODIES; precursor = PROINSULIN; INSULIN INFUSION SYSTEMS is available

Scope note

  • A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1).

In other languages

URI

http://www.yso.fi/onto/mesh/D007328

Download this concept:

RDF/XML TURTLE JSON-LD Created 1/1/99, last modified 6/24/11