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Concept information

Preferred term

Interferon-gamma  

Type

  • Topical Descriptor

Entry terms

  • gamma-Interferon
  • Immune Interferon
  • Interferon, gamma
  • Interferon, Immune
  • Interferon Type II
  • Interferon, Type II
  • Type II Interferon

Scope note

  • The major interferon produced by mitogenically or antigenically stimulated LYMPHOCYTES. It is structurally different from TYPE I INTERFERON and its major activity is immunoregulation. It has been implicated in the expression of CLASS II HISTOCOMPATIBILITY ANTIGENS in cells that do not normally produce them, leading to AUTOIMMUNE DISEASES.

History note

  • 2009(1983); INTERFERON-GAMMA was INTERFERON, GAMMA 1983-1990

In other languages

URI

http://www.yso.fi/onto/mesh/D007371

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