Concept information
...
Intercellular Signaling Peptides and Proteins
Cytokines
Lymphokines
Macrophage-Activating Factors
Preferred term
Interferon-gamma
Type
-
Topical Descriptor
Broader concept
Entry terms
- gamma-Interferon
- Immune Interferon
- Interferon, gamma
- Interferon, Immune
- Interferon Type II
- Interferon, Type II
- Type II Interferon
Scope note
- The major interferon produced by mitogenically or antigenically stimulated LYMPHOCYTES. It is structurally different from TYPE I INTERFERON and its major activity is immunoregulation. It has been implicated in the expression of CLASS II HISTOCOMPATIBILITY ANTIGENS in cells that do not normally produce them, leading to AUTOIMMUNE DISEASES.
History note
- 2009(1983); INTERFERON-GAMMA was INTERFERON, GAMMA 1983-1990
In other languages
-
Finnish
-
gamma-interferoni
-
interferoni tyyppi 2
-
tyypin 2 interferoni
-
Swedish
-
Interferon typ II
-
Quantiferon
URI
http://www.yso.fi/onto/mesh/D007371
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