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Concept information

Preferred term

Interleukin-1  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Epidermal Cell Derived Thymocyte Activating Factor
  • Epidermal Cell Derived Thymocyte-Activating Factor
  • IL-1
  • Interleukin I
  • Lymphocyte Activating Factor
  • Lymphocyte-Activating Factor
  • Macrophage Cell Factor
  • T Helper Factor

Scope note

  • A soluble factor produced by MONOCYTES; MACROPHAGES, and other cells which activates T-lymphocytes and potentiates their response to mitogens or antigens. Interleukin-1 is a general term refers to either of the two distinct proteins, INTERLEUKIN-1ALPHA and INTERLEUKIN-1BETA. The biological effects of IL-1 include the ability to replace macrophage requirements for T-cell activation.

History note

  • 1990(1983)

In other languages

URI

http://www.yso.fi/onto/mesh/D007375

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