Concept information
Preferred term
Aprotinin
Type
-
Topical Descriptor
Broader concept
Entry terms
- Basic Pancreatic Trypsin Inhibitor
- Bovine Kunitz Pancreatic Trypsin Inhibitor
- Bovine Pancreatic Trypsin Inhibitor
- BPTI, Basic Pancreatic Trypsin Inhibitor
- Inactivator, Kallikrein-Trypsin
- Kallikrein Trypsin Inactivator
- Kallikrein-Trypsin Inactivator
- Kunitz Pancreatic Trypsin Inhibitor
- Trypsin Inhibitor, Basic, Pancreatic
- Trypsin Inhibitor, Kunitz, Pancreatic
Scope note
- A single-chain polypeptide derived from bovine tissues consisting of 58 amino-acid residues. It is an inhibitor of proteolytic enzymes including CHYMOTRYPSIN; KALLIKREIN; PLASMIN; and TRYPSIN. It is used in the treatment of HEMORRHAGE associated with raised plasma concentrations of plasmin. It is also used to reduce blood loss and transfusion requirements in patients at high risk of major blood loss during and following open heart surgery with EXTRACORPOREAL CIRCULATION. (Reynolds JEF(Ed): Martindale: The Extra Pharmacopoeia (electronic version). Micromedex, Inc, Englewood, CO, 1995)
History note
- 90; was KALLIKREIN-TRYPSIN INACTIVATOR 1966-89
In other languages
URI
http://www.yso.fi/onto/mesh/D007611
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