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Concept information

Preferred term

Keratins  

Type

  • Topical Descriptor

Entry terms

  • Cytokeratin
  • Keratin

Scope note

  • A class of fibrous proteins or scleroproteins that represents the principal constituent of EPIDERMIS; HAIR; NAILS; horny tissues, and the organic matrix of tooth ENAMEL. Two major conformational groups have been characterized, alpha-keratin, whose peptide backbone forms a coiled-coil alpha helical structure consisting of TYPE I KERATIN and a TYPE II KERATIN, and beta-keratin, whose backbone forms a zigzag or pleated sheet structure. alpha-Keratins have been classified into at least 20 subtypes. In addition multiple isoforms of subtypes have been found which may be due to GENE DUPLICATION.

History note

  • 2007(1966)

In other languages

  • Finnish

  • ceratinum
  • keratiini
  • keratiinit
  • keratinum
  • Swedish

  • Alfa-keratin
  • Glykosylerad keratin
  • Keratin-associerade proteiner
  • Keratiner

URI

http://www.yso.fi/onto/mesh/D007633

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