Concept information
Preferred term
Keratins
Type
-
Topical Descriptor
Broader concept
Narrower concepts
Entry terms
- Cytokeratin
- Keratin
Scope note
- A class of fibrous proteins or scleroproteins that represents the principal constituent of EPIDERMIS; HAIR; NAILS; horny tissues, and the organic matrix of tooth ENAMEL. Two major conformational groups have been characterized, alpha-keratin, whose peptide backbone forms a coiled-coil alpha helical structure consisting of TYPE I KERATIN and a TYPE II KERATIN, and beta-keratin, whose backbone forms a zigzag or pleated sheet structure. alpha-Keratins have been classified into at least 20 subtypes. In addition multiple isoforms of subtypes have been found which may be due to GENE DUPLICATION.
History note
- 2007(1966)
In other languages
-
Finnish
-
ceratinum
-
keratiini
-
keratiinit
-
keratinum
-
Swedish
-
Alfa-keratin
-
Glykosylerad keratin
-
Keratin-associerade proteiner
-
Keratiner
URI
http://www.yso.fi/onto/mesh/D007633
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