Concept information
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Female Urogenital Diseases and Pregnancy Complications
Pregnancy Complications
Fetal Diseases
Erythroblastosis, Fetal
Congenital, Hereditary, and Neonatal Diseases and Abnormalities
Fetal Diseases
Erythroblastosis, Fetal
Preferred term
Kernicterus
Type
-
Topical Descriptor
Broader concept
Entry terms
- Bilirubin Encephalopathies
- Bilirubin Encephalopathy
- Encephalopathies, Bilirubin
- Encephalopathies, Hyperbilirubinemic
- Encephalopathy, Bilirubin
- Encephalopathy, Hyperbilirubinemic
- Hyperbilirubinemic Encephalopathies
- Hyperbilirubinemic Encephalopathy
Scope note
- A term used pathologically to describe BILIRUBIN staining of the BASAL GANGLIA; BRAIN STEM; and CEREBELLUM and clinically to describe a syndrome associated with HYPERBILIRUBINEMIA. Clinical features include athetosis, MUSCLE SPASTICITY or hypotonia, impaired vertical gaze, and DEAFNESS. Nonconjugated bilirubin enters the brain and acts as a neurotoxin, often in association with conditions that impair the BLOOD-BRAIN BARRIER (e.g., SEPSIS). This condition occurs primarily in neonates (INFANT, NEWBORN), but may rarely occur in adults. (Menkes, Textbook of Child Neurology, 5th ed, p613)
In other languages
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Finnish
-
encephalopathia e bilirubino
-
icterus non specificatus
-
icterus nuclearis
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kernicterus
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määrittämätön kernikterus
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Swedish
URI
http://www.yso.fi/onto/mesh/D007647
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