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Concept information

Preferred term

Killer Cells, Natural  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Cell, Natural Killer
  • Cell, NK
  • Cells, Natural Killer
  • Cells, NK
  • Killer Cell, Natural
  • Natural Killer Cell
  • Natural Killer Cells
  • NK Cell
  • NK Cells

Note

  • do not confuse with NATURAL KILLER T-CELLS; if subpopulations are discussed, coordinate IM with LYMPHOCYTE SUBSETS (IM)

Scope note

  • Bone marrow-derived lymphocytes that possess cytotoxic properties, classically directed against transformed and virus-infected cells. Unlike T CELLS; and B CELLS; NK CELLS are not antigen specific. The cytotoxicity of natural killer cells is determined by the collective signaling of an array of inhibitory and stimulatory CELL SURFACE RECEPTORS. A subset of T-LYMPHOCYTES referred to as NATURAL KILLER T CELLS shares some of the properties of this cell type.

History note

  • 1983

In other languages

URI

http://www.yso.fi/onto/mesh/D007694

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