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Biological Factors > Blood Coagulation Factors > Kininogens
Amino Acids, Peptides, and Proteins > Proteins > Blood Proteins > Blood Coagulation Factors > Kininogens
Amino Acids, Peptides, and Proteins > Proteins > Protein Precursors > Kininogens
Biological Factors > Inflammation Mediators > Autacoids > Kinins > Kininogens
Biological Factors > Intercellular Signaling Peptides and Proteins > Kinins > Kininogens
Amino Acids, Peptides, and Proteins > Proteins > Intercellular Signaling Peptides and Proteins > Kinins > Kininogens
Amino Acids, Peptides, and Proteins > Peptides > Intercellular Signaling Peptides and Proteins > Kinins > Kininogens

Preferred term

Kininogens  

Type

  • Topical Descriptor

Broader concept

Narrower concepts

Entry terms

  • Cystatins, Kininogen
  • Kininogen Cystatins
  • Prekinins
  • Prokinins

Note

  • cysteine proteinase inhib; /drug eff /physiol permitted

Scope note

  • Endogenous peptides present in most body fluids. Certain enzymes convert them to active KININS which are involved in inflammation, blood clotting, complement reactions, etc. Kininogens belong to the cystatin superfamily. They are cysteine proteinase inhibitors. HIGH-MOLECULAR-WEIGHT KININOGEN; (HMWK); is split by plasma kallikrein to produce BRADYKININ. LOW-MOLECULAR-WEIGHT KININOGEN; (LMWK); is split by tissue kallikrein to produce KALLIDIN.

History note

  • 74(72)

In other languages

URI

http://www.yso.fi/onto/mesh/D007704

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