Concept information
Preferred term
Phosphatidylcholine-Sterol O-Acyltransferase
Type
-
Topical Descriptor
Broader concept
Entry terms
- Acyltransferase, Lecithin
- Acyltransferase, Lecithin Cholesterol
- Acyltransferase, Phosophatidylcholine-Sterol
- Cholesterol Acyltransferase, Lecithin
- Cholesterol Ester Lysolecithin Acyltransferase
- Lecithin Acyltransferase
- Lecithin Cholesterol Acyltransferase
- Phosophatidylcholine Sterol Acyltransferase
- Phosophatidylcholine-Sterol Acyltransferase
Scope note
- An enzyme secreted from the liver into the plasma of many mammalian species. It catalyzes the esterification of the hydroxyl group of lipoprotein cholesterol by the transfer of a fatty acid from the C-2 position of lecithin. In familial lecithin:cholesterol acyltransferase deficiency disease, the absence of the enzyme results in an excess of unesterified cholesterol in plasma.
History note
- 98(75)
In other languages
URI
http://www.yso.fi/onto/mesh/D007862
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