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Investigative Techniques > Clinical Laboratory Techniques > Immunologic Tests > Histocompatibility Testing > Lymphocyte Culture Test, Mixed
... > Diagnosis > Diagnostic Techniques and Procedures > Clinical Laboratory Techniques > Immunologic Tests > Histocompatibility Testing > Lymphocyte Culture Test, Mixed
Investigative Techniques > Immunologic Techniques > Immunologic Tests > Histocompatibility Testing > Lymphocyte Culture Test, Mixed

Preferred term

Lymphocyte Culture Test, Mixed  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Leukocyte Culture Test, Mixed
  • Leukocyte Reaction, Mixed
  • Leukocyte Reactions, Mixed
  • Lymphocyte Reaction, Mixed
  • Lymphocyte Reactions, Mixed
  • Mixed Leukocyte Culture Test
  • Mixed Leukocyte Reaction
  • Mixed Leukocyte Reactions
  • Mixed Lymphocyte Culture Test
  • Mixed Lymphocyte Reaction
  • Mixed Lymphocyte Reactions

Note

  • NIM

Scope note

  • Measure of histocompatibility at the HL-A locus. Peripheral blood lymphocytes from two individuals are mixed together in tissue culture for several days. Lymphocytes from incompatible individuals will stimulate each other to proliferate significantly (measured by tritiated thymidine uptake) whereas those from compatible individuals will not. In the one-way MLC test, the lymphocytes from one of the individuals are inactivated (usually by treatment with MITOMYCIN or radiation) thereby allowing only the untreated remaining population of cells to proliferate in response to foreign histocompatibility antigens.

History note

  • 93; was LEUKOCYTE CULTURE TEST, MIXED 1973-92; LYMPHOCYTE CULTURE TEST, MIXED was see LEUKOCYTE CULTURE TEST, MIXED 1981-92

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URI

http://www.yso.fi/onto/mesh/D007959

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